Our mIHC data analysis services provide deep insights into the immune landscape, tumor microenvironment, and cellular interactions. With our expertise, you can accurately quantify and visualize key cellular markers across various tissue types, including but not limited to cancer research.

Our Services Include:

l Standard Quantification

Precise analysis of single-positive and multi-positive cells (e.g., CD3+, CD4+, CD8+, CD20+, CD21+, CD23+).

Quantify total cell count, percentage of positive cells, average fluorescence intensity, and cell area for a deeper understanding of cellular distributions.

l Tissue Morphology Recognition & Quantification

Identify and quantify specific tissue structures such as tumors, lymph nodes, blood vessels, and glomeruli.

Provide critical data on the area, density, and distribution of key structures, offering insights into disease progression, prognosis, and response to treatment.

l Advanced Spatial Analysis Modules

Cell-Cell Proximity Analysis: Understand cellular interactions by evaluating the distance between different cell types (e.g., T cells in proximity to tumor cells), helping assess immune cell infiltration and function.

Infiltration Analysis: Quantify cell infiltration within specific tissue regions (e.g., tumor boundary), with insights on immune cell distribution and density in response to therapy.

Organ-Specific Analysis: Assess cell distribution within different tissue zones, such as the spatial arrangement of immune cells in tertiary lymphoid structures (TLS), reflecting their functional state.

l Cluster Recognition & Feature Analysis

Identify and analyze cell aggregates (e.g., TLS, tumor cell clusters), calculating the number, density, and average cell count per cluster.

Correlate the presence and density of immune cell clusters with treatment responses, offering a predictive biomarker for therapeutic efficacy.

l Additional Advanced Analysis Options

Heatmap Analysis: Generate heatmaps to visually compare cell distribution densities across tissue sections, providing intuitive insights into cell behavior and immune response.

FISH Dot Recognition: Detect and quantify fluorescent in situ hybridization (FISH) dots, offering precise spatial localization of genetic markers or specific target cells in tissue samples.

Microglia Quantification: Analyze and quantify microglia cell populations in the brain or other nervous tissues, providing insights into immune responses in the central nervous system.

Continuous Slide Stacking & Quantification: Combine consecutive tissue slices to create high-resolution, multi-dimensional images and perform quantitative analysis of complex tissue interactions and structures across multiple layers.

Hub Analysis: Identify and analyze immune cell interactions within specific hubs, such as T cell and dendritic cell clusters. By mapping and quantifying these hubs, we can assess the potential of direct immune cell killing and overall immune response efficacy.

Customizable Solutions

Tailored analysis according to your specific research needs, whether you're studying immune response, tumor microenvironment, disease progression, or therapeutic outcomes.

High-quality, reproducible data that enhances your research accuracy and provides valuable insights for clinical and experimental studies.

Why Choose Our Services?

Comprehensive: From immune cell profiling to advanced spatial and morphological analysis.

Precise: Accurate, quantitative data for all your research needs.

Custom: Solutions tailored to meet the unique needs of your research project.

Ready to elevate your research with advanced mIHC data analysis? Contact us today for personalized service and high-impact insights!